|Venue: Franklin’s Gardens Date: Saturday, 17 November Kick-off: 13:00 GMT Coverage: BBC local radio and the BBC Sport website|
Northampton flanker Tom Wood makes his first Premiership appearance since March after a pelvic injury.
George Furbank, Fraser Dingwall and Alex Moon all make their first league starts for the injury-hit hosts.
Wasps back row Ashley Johnson returns to captain the side, with Juan de Jongh also recalled at centre.
Academy youngster Tom Willis is in line for his first Premiership start, Kieran Brookes faces his old side and Jake Cooper-Woolley is named on the bench.
Northampton: Furbank; Kellaway, Dingwall, Francis, Naiyaravoro; Grayson, Reinach; Waller (capt), Fish, Franks, Ribbans, Moon, Wood, Ludlam, Harrison
Replacements: Marshall, Davis, Garside, Ratuniyarawa, Gibson, Mitchell, Burrell, Sleightholme
Wasps: Miller; Watson, De Jongh, Lovobalavu, Bassett; Sopoaga, Simpson; Harris, Cruse, Brookes, Rowlands, Gaskell, Johnson (capt), Young, Willis
Replacements: Harris, West, Cooper-Woolley, Myall, Morris, Hampson, Searle, Le Bourgeois