|Venue: Sandy Park Date: Saturday, 24 November Kick-off: 13:00 GMT Coverage: BBC local radio and the BBC Sport website|
Premiership leaders Exeter Chiefs replace Tom Lawday to the first of three games against Gloucester and Dave Ewers using Ollie Atkins and forwards Dave Dennis before Christmas.
For Stu Townsend since the change Nic White comes in in the halves to the backline.
Henry Walker, Val Rapava Ruskin and Ben Morgan come in the Gloucester package.
Henry Trinder returns in the three-quarters while Charlie Sharples comes onto the wing.
Having been paired in the same Champions Cup group, the two teams meet again next month home and away.
While Gloucester are third but 11 points behind, chiefs are high in the Premiership, before Saracens on points difference.
Gloucester: Woodward; Sharples, Trinder, Twelvetrees, Thorley; Cipriani, Heinz; Rapava Ruskin, Walker, Balmain, Savage, Slater, Clarke, Evans, Morgan
Replacements: Visagie, Traynor, Hohneck, Grobler, Hinkley, Braley, Williams, Hudson