|European Rugby Champions Cup|
|Venue: Matmut Stadium de Gerland Date: Sunday, 13 January Kickoff: 15:15 GMT|
|Coverage: Live score updates on BBC local radio and Also on the BBC Sport website|
Second row Maro Itoje returns for Saracens after stripping his kneecap at England’s autumn Test series.
Fellow British and Irish Lion Jamie George is back at hooker after being rested to the defeat Sale.
Jackson Wray replaces Nick Isiekwe at Blind Side flanker while Sean Maitland comes in for David Strettle on the wing.
Lyon’s Line up comprises France wings Noa Nakaitaci along with Alexis Palisson along with Jonathan WISniewski at Flyhalf.
Saracens, who lifted the prize at 2016 and 2017, are just four points clear on very top of Pool Three after winning their opening four matches in this season’s effort.
Lyon have lost all of the matches, for example a 29-10 defeat from the reverse fixture at Allianz Park in October. However, Les Loups are unbeaten at home in the Top 14.
“It is definitely hard with French teams as they take a lot of pride within their house ground so I suppose we do not need a great deal more motivation than that,” said number eight Billy Vunipola.
“Perhaps if we kid ourselves and think that we’ll be OK if we only think of ourselves we’re most likely to slide upward. We need to come out with the ideal attitude and that’s from everyone, and focus on our tasks hand, but be ready for a garbage”
Lozowski, Williams; Farrell, Wigglesworth; M Vunipola, George, Koch, Itoje, Kruis, Wray, Burger, B Vunipola.
Replacements: Tolofua, Barrington, Judge, Skelton, Earl, Spence, Bosch, Strettle
Lyon: Arnold; Nakaitaci, Barassi, Regard, Palisson; WISniewski, Doussain; Menini, Lacombe, Gomez Kodela, Roodt, Van der Merwe, Puricelli (captain), Cretin, Fourie.
Replacements: Maurouard, Buckle, Yameogo, Oosthuizen, Gill, Wulf, Buttin, McLeod.