Ireland coach Joe Schmidt said straight back row Stander had gone for a scan onto a facial injury and that wing Earls had been forced off by way of a hip injury.
“CJ Stander we presume has a facial injury and has gone to some scan.”
Schmidt added that lock Devin Toner had”revived his arm” when landing after catching a kickoff because Ireland’s hopes of achieving back to back Grand Slams were ended in emphatic manner by Eddie Jones’ side.
After being on the receiving end of large tackles from Maro Itoje and Tom Curry, Jordan Larmour in half-time replaced earls.
Curry has been sin-binned by referee Jerome Garces for his struggle Earls with Itoje devoting a penalty in the second incident.
Asked about Itoje’s handle on Earls,” Schmidt responded:”I am not likely to get into any discussions relating to this. I’m going to have the normal channels.
“I am just going to ask for some clarification on several of those incidents we watched and once I get that people’ll have a much better, clearer picture and we’ll have a better anticipation of exactly what referees are in fact going to deliver concerning player safety after which we can spring board from that point.
“It got quite physical but that I really don’t believe necessarily that was part of a plan. It surely placed Keith out of the game and he was experienced back-three player,” added the Ireland coach.
Andrew Conway, Will Addison and Adam Byrne would be one of Schmidt’s wing options along with Larmour if Earls is ruled out.
Stander was replaced by sean O’Brien after 65 minutes from Saturday’s bruising contest while Jordi Murphy, Rhys Ruddock and Jack Conan could be to be drafted in the Murrayfield squad.