|Venue: Stadio Olimpico, Rome Date: Saturday, 9 February Kick off: 16:45 GMT|
Flankers Thomas Young and Aaron Wainwright, wing Jonah Holmes and Scrum Half Aled Davies make their first starts.
Josh Navidi goes to number eight along side usual captain Alun Wyn Jones, with Ross Moriarty dropping to the bench.
Edoardo Padovani starts in one of two changes on the wing to Italy.
Wasps rear Michele Campagnaro moves into centre to make a 40th limit, while Benetton prop Nicola Quaglio replaces Andrea Lovotti to create just a third beginning.
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View from the Wales camp
Wales head coach Warren Gatland: “We’ve made a number of changes, however chose exactly what we think is a very exciting team which still has huge experience throughout it.
“We’ve made a related number of changes into that which we did last year, however it’s about chance for these players. We have experienced a squad of 31 training copying the Rugby World Cup, and it’s necessary they get game timing.
“It’s is a great chance to get Jon as captain. He has a enormous volume of experience, is a excellent pioneer and it’s a fantastic honour for him.
“Italy is likely to likely soon be damaging after last weekend however they’re an alternative proposal in Rome.”
Head to Head
- Wales have won their last 11 meetings with Italy at the Six Nations, scoring a mean of 36 points per game.
- Italy have conquered Wales at home on two occasions from the Six Nations. They succeeded 23-20 in 30-22 and 2007 at 2003.
- Wales’ biggest-ever six-nations triumph was against Italy, a 67-14 dwelling triumph in 20-16.
- Italy have lost their last 18 games in this championship – a Five/Six Nations record.
- They have conceded 751 points, an average of 42 per game, during that run.
- Italy have triumphed in just six games as the 2015 World Cup, losing 28.
- Wales may match their best-ever run of 11 straight Test wins, last place in 1910.
- Their 16-point turn around at the triumph over France last weekend was the biggest half-time comeback in any ten or Five Nations game.
- It was the biggest half-time come back in Welsh Test history.
- Ross Moriarty and Justin Tipuric made a joint game-high 20 tackles in the triumph over France last weekend.