|US Open 2019|
|Venue: Flushing Meadows, New York Dates: 26 Aug – 8 Sep|
|Coverage: Live text and BBC Radio 5 Live Sports Extra commentary on selected matches on the BBC Sport website and app. Click here for Live Guide.|
Edmund fought back from behind to take a fluctuating match into a decider.
But his service game deserted him in the final set as Spaniard Andujar won 3-6 7-6 (7-1) 7-5 5-7 6-2 in four hours 21 minutes – the longest match at this year’s tournament so far.
Johanna Konta and Dan Evans are now the only Britons left in the singles.
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Edmund, the 30th seed, led by a set and a break against 33-year-old Andujar before his grip on the match was loosened by an increasing number of unforced errors.
The 24-year-old Yorkshireman steadied his game – built around that explosive forehand – to take a fourth set, where 25 winners outnumbered 11 mistakes off his racquet.
Edmund had only taken four of 12 break points in the match before finally finding a ruthless edge when he needed to most.
On Andujar’s serve at 6-5 in the fourth, Edmund walloped three winners to tee up three break points and took the match into a decider at the first opportunity with another precise backhand which left his opponent wafting.
But all that hard work was undone by a poor final set where fatigue in warm New York conditions, albeit nowhere near as hot and humid as last year, may have contributed.
Initially it looked as though Edmund would go on to win after he broke in the second game, only for the Briton’s game to quickly unravel.
After Andujar immediately broke back, Edmund was eventually outfought in a fifth game where he had saved four break points and from that moment his hopes evaporated.
Andujar, never ranked inside the world’s top 30, powered an ace down the middle to set up two match points, needing just the first when Edmund’s day was summed up by a framed backhand which flew off court.